Research:
Diet and cancer prevention

Teaching:
Diet and disease prevention and treatment

Interests:
Oxidative stress may contribute to the development of chronic diseases such as cancer and heart disease. One area of Dr. Fischer's research has focused on the effect of nutrients such as iron and vitamin E on antioxidant status, oxidative stress, and biomarkers associated with colon and liver cancer development. Recent studies have also included flavonoids, antioxidant compounds found in fruits and vegetables. Another research interest is the examination of food and nutrient intakes of elderly individuals.

Education:

Selected Publications/Presentations:
Yi, W., Fischer, J., Akoh, C.C. (2005) Study of anticancer activities of muscadine grape phenolics in vitro. Journal of Agricultural and Food Chemistry, 53, 8804-8812.

Yi, W., Fischer, J., Krewer, G., Akoh, C.C. (2005) Phenolic Compounds from Blueberries Can Inhibit Colon Cancer Cell Proliferation and Induce Apoptosis. Journal of Agricultural and Food Chemistry, 53, 7320 - 7329.

Ellis, J., Johnson, M.A., Fischer, J.G., Hargrove, J.L. (2005) Nutrition and Health Education Intervention for Whole Grain Foods in the Georgia Older Americans Nutrition Program. Journal of Nutrition for the Elderly, 24, 67-84.

Bales, C.W., Fischer, J.G., Orenduff, M.C. (2004) Nutritional Interventions for Age-Related Chronic Disease. Generations: Journal of the American Society on Aging, 28, 54-60.

Cheong, J.M.K., Johnson, M.A., Lewis, R.D., Fischer, J.G., Johnson, J.T. (2003) Reduction in modifiable osteoporosis-related risk factors among adults in the Older Americans Nutrition Program. Family Economics and Nutrition Review, 15, 83-91.

Johnson, M.A., Hawthorne, N.A., Brackett, W.R., Fischer, J.G., Gunter, E. W., Allen, R.H., & Stabler, S. P. (2003) Hyperhomocysteinemia and vitamin B12 deficiency in Elders using Title IIIc Nutrition Services. American Journal of Clinical Nutrition, 77, 211-220.

Fischer, J.G., Glauert, H.P., Yin, T., Sweeney-Reeves, M.L., Larmonier, N., Black, M.C. (2002) Moderate iron overload enhances lipid peroxidation in livers of rats, but does not affect NF-kappaB activation induced by the peroxisome proliferator, Wy 14,643. Journal of Nutrition, 132, 2525-2531.

Wright, M.O., Burden, V., Lee, J., Eitenmiller, R.R., Fischer, J.G. (1999). High dietary iron enhances oxidative stress in liver, but does not increase aberrant foci development in rats with low vitamin E status. Nutrition and Cancer, 35, 143-152.

Soyars, K.E., & Fischer, J.G. (1998). Iron Supplementation Does Not Affect Cell Proliferation or Aberrant Crypt Foci Development in the Colon of Sprague Dawley Rats. Journal of Nutrition, 128, 764- 70.

Stimson, J., Fischer, J.G. (1997) Iron Intake Affects Lipid Peroxidation and Glutathione Peroxidase Activity of Distal Colonic Mucosa. Nutrition Research, 17, 1683-91.

Fischer, J. G., Johnson, M. A., Poon, L. W., & Martin, P. (1995). Dairy product intake of the oldest old. Journal of American Dietetic Association, 95, 918-920.

Johnson, M. A., Fischer, J. G., Bowman, B. A., Gunter, E. W. (1994). Iron nutriture in elderly individuals. FASEB J., 8, 609-621.